Effects of IKur blocker MK-0448 on human right atrial action potentials from pateints in sinus rhythm and in permanent atrial fibrillation.

Selective blockers of the Kv1.5 channel have been developed for the treatment of atrial fibrillation (AF), but little is known how these atrial-selective drugs affect human action potentials (APs). Therefore we have investigated the Kv1.5 blocker MK-0448 (N-{6-[(1S)-1-(4-fluorophenyl)-2,2-di(pyridin...

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主要な著者: Simone eLoose (著者), Judith eMueller (著者), Erich eWettwer (著者), Michael eKnaut (著者), John eFord (著者), James eMilnes (著者), Ursula eRavens (著者)
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出版事項: Frontiers Media S.A., 2014-03-01T00:00:00Z.
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