Effects of IKur blocker MK-0448 on human right atrial action potentials from pateints in sinus rhythm and in permanent atrial fibrillation.

• 主要な著者: Simone eLoose (著者), Judith eMueller (著者), Erich eWettwer (著者), Michael eKnaut (著者), John eFord (著者), James eMilnes (著者), Ursula eRavens (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2014-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Selective blockers of the Kv1.5 channel have been developed for the treatment of atrial fibrillation (AF), but little is known how these atrial-selective drugs affect human action potentials (APs). Therefore we have investigated the Kv1.5 blocker MK-0448 (N-{6-[(1S)-1-(4-fluorophenyl)-2,2-di(pyridin...