Stereoselective inhibition of the hERG1 potassium channel
A growing number of drugs have been shown to prolong cardiac repolarization, predisposing individuals to life-threatening ventricular arrhythmias known as Torsades de Pointes. Most of these drugs are known to interfere with the human ether à-gogo related gene 1 (hERG1) channel, whose curren...
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| Main Authors: | , , |
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| Format: | Book |
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Frontiers Media S.A.,
2010-11-01T00:00:00Z.
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