Targeted Protein Degradation by Chimeric Compounds using Hydrophobic E3 Ligands and Adamantane Moiety
Targeted protein degradation using small chimeric molecules, such as proteolysis-targeting chimeras (PROTACs) and specific and nongenetic inhibitors of apoptosis protein [IAP]-dependent protein erasers (SNIPERs), is a promising technology in drug discovery. We recently developed a novel class of chi...
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Main Authors: | Takuji Shoda (Author), Nobumichi Ohoka (Author), Genichiro Tsuji (Author), Takuma Fujisato (Author), Hideshi Inoue (Author), Yosuke Demizu (Author), Mikihiko Naito (Author), Masaaki Kurihara (Author) |
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Format: | Book |
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MDPI AG,
2020-02-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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