Analysis of sequence variations in the suppressor of cytokine signaling (<it>SOCS</it>)<it>-3 </it>gene in extremely obese children and adolescents

• Main Authors: Goldschmidt Hanspeter (Author), Siegfried Wolfgang (Author), Scherag André (Author), Wermter Anne-Kathrin (Author), Hölter Katja (Author), Hebebrand Johannes (Author), Hinney Anke (Author)
• Format: Book
• Published: BMC, 2007-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>The suppressor of cytokine signaling (SOCS)-3 is a negative feedback regulator of cytokine signaling and also influences leptin signaling. We investigated association of variations in the coding sequence and promoter region of <it...