A Comprehensive Physiologically Based Pharmacokinetic Model of Nadolol in Adults with Renal Disease and Pediatrics with Supraventricular Tachycardia

• Päätekijät: Samia Kalsoom (Tekijä), Muhammad Fawad Rasool (Tekijä), Imran Imran (Tekijä), Hamid Saeed (Tekijä), Tanveer Ahmad (Tekijä), Faleh Alqahtani (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: MDPI AG, 2024-02-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Nadolol is a long-acting non-selective β-adrenergic antagonist that helps treat angina and hypertension. The current study aimed to develop and validate the physiologically based pharmacokinetic model (PBPK) of nadolol in healthy adults, renal-compromised, and pediatric populations. A comprehensive...