Meropenem Stability in Human Plasma at −20 °C: Detailed Assessment of Degradation

• मुख्य लेखकों: Matthias Gijsen (लेखक), Benjamin Filtjens (लेखक), Pieter Annaert (लेखक), Yeghig Armoudjian (लेखक), Yves Debaveye (लेखक), Joost Wauters (लेखक), Peter Slaets (लेखक), Isabel Spriet (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

There are concerns about the stability of meropenem in plasma samples, even when frozen at −20 °C. Previous smaller studies suggested significant degradation of meropenem at −20 °C after 3-20 days. However, in several recent clinical studies, meropenem plasma samples were still stored at −20 °C, or...