Nanobody-Based Biologics for Modulating Purinergic Signaling in Inflammation and Immunity
Adenosine triphosphate (ATP) and nicotinamide adenine dinucleotide (NAD+) are released as danger signals from cells during infection and sterile inflammation. In the extracellular compartment ATP is converted by CD39, CD73, and other ecto-enzymes into metabolites that modulate the activity of T cell...
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Format: | Book |
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Frontiers Media S.A.,
2018-03-01T00:00:00Z.
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A1234.567 |
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