Microbe-Derived Antioxidants Protect IPEC-1 Cells from H₂O₂-Induced Oxidative Stress, Inflammation and Tight Junction Protein Disruption via Activating the Nrf2 Pathway to Inhibit the ROS/NLRP3/IL-1β Signaling Pathway

• Main Authors: Cheng Shen (Author), Zhen Luo (Author), Sheng Ma (Author), Chengbing Yu (Author), Ting Lai (Author), Shangshang Tang (Author), Hongcai Zhang (Author), Jing Zhang (Author), Weina Xu (Author), Jianxiong Xu (Author)
• Format: Book
• Published: MDPI AG, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress can induce inflammation and tight junction disruption in enterocytes. The initiation of inflammation is thought to commence with the activation of the ROS/NLRP3/IL-1β signaling pathway, marking a crucial starting point in the process. In our previous studies, we found that microbe-d...