Dihydroquercetin Activates AMPK/Nrf2/HO-1 Signaling in Macrophages and Attenuates Inflammation in LPS-Induced Endotoxemic Mice

• Hoofdauteurs: Liming Lei (Auteur), Yunfei Chai (Auteur), Haoming Lin (Auteur), Chunbo Chen (Auteur), Mingyi Zhao (Auteur), Weiping Xiong (Auteur), Jian Zhuang (Auteur), Xiaoping Fan (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2020-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Dihydroquercetin (DHQ) is a flavonoid compound known for its anti-oxidant effects. Oxidative stress plays a dominant role in regulating the pathways associated with systemic inflammatory immune activation during endotoxemia. Whether and how DHQ regulates inflammatory responses in endotoxemia remains...