Synthesis, characterisation, biological evaluation and in silico studies of sulphonamide Schiff bases

• Main Authors: Mustafa Durgun (Author), Cüneyt Türkeş (Author), Mesut Işık (Author), Yeliz Demir (Author), Ali Saklı (Author), Ali Kuru (Author), Abdussamat Güzel (Author), Şükrü Beydemir (Author), Suleyman Akocak (Author), Sameh M. Osman (Author), Zeid AlOthman (Author), Claudiu T. Supuran (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sulphonamides are biologically important compounds with low toxicity, many bioactivities and cost-effectiveness. Eight sulphonamide derivatives were synthesised and characterised by FT-IR, 13C NMR, 1H NMR, LC-MS and elemental analysis. Their inhibitory effect on AChE, and carbonic anhydrase I and II...