Flexibility of oral cholera vaccine dosing-a randomized controlled trial measuring immune responses following alternative vaccination schedules in a cholera hyper-endemic zone.

• Main Authors: Suman Kanungo (Author), Sachin N Desai (Author), Ranjan Kumar Nandy (Author), Mihir Kumar Bhattacharya (Author), Deok Ryun Kim (Author), Anuradha Sinha (Author), Tanmay Mahapatra (Author), Jae Seung Yang (Author), Anna Lena Lopez (Author), Byomkesh Manna (Author), Barnali Bannerjee (Author), Mohammad Ali (Author), Mandeep Singh Dhingra (Author), Ananga Mohan Chandra (Author), John D Clemens (Author), Dipika Sur (Author), Thomas F Wierzba (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:A bivalent killed whole cell oral cholera vaccine has been found to be safe and efficacious for five years in the cholera endemic setting of Kolkata, India, when given in a two dose schedule, two weeks apart. A randomized controlled trial revealed that the immune response was not signific...