The lncRNA-GAS5/miR-221-3p/DKK2 Axis Modulates ABCB1-Mediated Adriamycin Resistance of Breast Cancer via the Wnt/β-Catenin Signaling Pathway

• Auteurs principaux: Zhaolin Chen (Auteur), Tingting Pan (Auteur), Duochen Jiang (Auteur), Le Jin (Auteur), Yadi Geng (Auteur), Xiaojun Feng (Auteur), Aizong Shen (Auteur), Lei Zhang (Auteur)
• Format: Livre
• Publié: Elsevier, 2020-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Drug resistance, including adriamycin (ADR)-based therapeutic resistance, is a crucial cause of chemotherapy failure in breast cancer treatment. Acquired chemoresistance has been identified to be closely associated with the overexpression of P-glycoprotein (P-gp/ABCB1). Long non-coding RNA (lncRNA)...