Effects of Sophora flavescens aiton and the absorbed bioactive metabolite matrine individually and in combination with 5-fluorouracil on proliferation and apoptosis of gastric cancer cells in nude mice

• Main Authors: Huan-Fu Hu (Author), Zheng Wang (Author), Wen-Li Tang (Author), Xue-Ming Fu (Author), Xiang-Jun Kong (Author), Ying-Kun Qiu (Author), Sheng-Yan Xi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:Sophora flavescens aiton (SFA) and its main bioactive metabolite matrine are widely used in traditional Chinese medicine (TCM) preparations and have achieved good curative effects for the treatment of various tumors. However, the mechanisms underlying SFA and matrine individually and in c...