Folliculin Interacts with Rab35 to Regulate EGF-Induced EGFR Degradation

• Main Authors: Jianchao Zheng (Author), Biao Duan (Author), Shixiu Sun (Author), Jie Cui (Author), Jun Du (Author), Yujie Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aims and Hypothesis: This study aims to investigate the mechanism involved in intracellular regulation of EGFR degradation induced by EGF.Methods: Phosphorylation of proteins related to EGFR signaling was examined by western blot analysis. Activation, connection between Rab35 and folliculin (FLCN) w...