Model-Informed Translation of In Vitro Effects of Short-, Prolonged- and Continuous-Infusion Meropenem against <em>Pseudomonas aeruginosa</em> to Clinical Settings

Pharmacokinetic-pharmacodynamic (PKPD) models have met increasing interest as tools to identify potential efficacious antibiotic dosing regimens in vitro and in vivo. We sought to investigate the impact of diversely shaped clinical pharmacokinetic profiles of meropenem on the growth/killing patterns...

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Main Authors: Iris K. Minichmayr (Author), Suzanne Kappetein (Author), Margreke J. E. Brill (Author), Lena E. Friberg (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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