An Overview of the Development and Preclinical Evaluation of Antibody-Drug Conjugates for Non-Oncological Applications

• Main Authors: Lal Bahadur Pal (Author), Prajakta Bule (Author), Wahid Khan (Author), Naveen Chella (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Typically, antibody-drug conjugates (ADCs) are made up of a humanized antibody and a small-molecule medication connected by a chemical linker. ADCs' ability to deliver cytotoxic agents to the specific site with reduced side effects showed promising results in oncology. To date, fourteen ADCs ha...