In vitro metabolic profile and drug‐drug interaction assessment of secnidazole, a high‐dose 5‐nitroimidazole antibiotic for the treatment of bacterial vaginosis

Abstract A single‐dose oral granule formulation of secnidazole 2 g (SOLOSEC™) has been approved in the US as a treatment for bacterial vaginosis. Available data on the likelihood of in vitro drug‐drug and alcohol‐drug interactions are limited. Secnidazole was incubated with cultured human hepatocyte...

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Main Authors: Helen S. Pentikis (Author), Nikki Adetoro (Author), Gregory Kaufman (Author)
Format: Book
Published: Wiley, 2020-08-01T00:00:00Z.
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3rd Floor Main Library

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