Tilianin suppresses NLRP3 inflammasome activation in myocardial ischemia/reperfusion injury via inhibition of TLR4/NF-κB and NEK7/NLRP3

• Main Authors: Suyue Yin (Author), Kaixi Han (Author), Di Wu (Author), Zihan Wang (Author), Ruifang Zheng (Author), Lianhua Fang (Author), Shoubao Wang (Author), Jianguo Xing (Author), Guanhua Du (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tilianin, a flavonoid compound derived from Dracocephalum moldavica L., is recognized for its diverse biological functionalities, in particular alleviating myocardial ischemia-reperfusion injury (MIRI). There is ample evidence suggesting that the NLRP3 inflammasome has a significant impact on the de...