Piperlongumine is a ligand for the orphan nuclear receptor 4A1 (NR4A1)
Piperlongumine and derivatives are being developed as anticancer agents which act primarily as inducers of reactive oxygen species (ROS) in cancer cell lines. Many of the anticancer activities of piperlongumine resemble those observed for bis-indole derived compounds that bind the orphan nuclear rec...
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Frontiers Media S.A.,
2023-09-01T00:00:00Z.
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