Sedative-hypnotic effect of YZG-330 and its effect on chloride influx in mouse brain cortical cells

• Main Authors: Lili Liu (Author), Shaobo Jia (Author), Jingwen Dong (Author), Ying Zhang (Author), Ruiming Xu (Author), Jianjun Zhang (Author)
• Format: Book
• Published: Elsevier, 2013-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study was to examine the sedative-hypnotic effect of YZG-330 and its influence on Cl− influx in mouse cortical cells. In a sleep time-prolongation test in which mice were administered a threshold dosage of sodium pentobarbital (ip), YZG-330 (0.125, 0.5 and 2 mg/kg, po) prolonged the sleep time...