Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo

• Päätekijät: Yuhan Liu (Tekijä), Jiabin Zhou (Tekijä), Yingying Luo (Tekijä), Jinxiao Li (Tekijä), Luorui Shang (Tekijä), Fangyuan Zhou (Tekijä), Shenglan Yang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2021-11-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Honokiol (HKL) has been reported to ameliorate lipopolysaccharide (LPS)-induced acute lung injury (ALI). However, its potential mechanism of its protective effects remains unclear. In this study, the protective mechanism of HKL on LPS-induced ALI was explored in vivo and in vitro...