In silico identification and experimental validation of cellular uptake and intracellular labeling by a new cell penetrating peptide derived from CDN1

• Main Authors: Xiangli Guo (Author), Linlin Chen (Author), Lidan Wang (Author), Jingping Geng (Author), Tao Wang (Author), Jixiong Hu (Author), Jason Li (Author), Changbai Liu (Author), Hu Wang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bioactive therapeutic molecules are generally impermeable to the cell membrane, hindering their utility and efficacy. A group of peptides called cell-penetrating peptides (CPPs) were found to have the capability of transporting different types of cargo molecules across the cell membrane. Here, we id...