Topical tissue nanotransfection of Prox1 is effective in the prophylactic management of lymphedema

• Main Authors: Ganesh Mohan (Author), Imran Khan (Author), Colby R. Neumann (Author), Miguel D. Jorge (Author), Shahnur Ahmed (Author), Luci Hulsman (Author), Mithun Sinha (Author), Gayle M. Gordillo (Author), Chandan K. Sen (Author), Aladdin H. Hassanein (Author)
• Format: Book
• Published: Elsevier, 2024-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Lymphedema is chronic limb swelling resulting from lymphatic dysfunction. There is no cure for the disease. Clinically, a preventive surgical approach called immediate lymphatic reconstruction (ILR) has gained traction. Experimental gene-based therapeutic approaches (e.g., using viral vectors) have...