Antiretroviral drugs from multiple classes induce loss of excitatory synapses between hippocampal neurons in culture

• मुख्य लेखकों: Hannah M. McMullan (लेखक), Benjamin M. Gansemer (लेखक), Stanley A. Thayer (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Antiretroviral (ARV) drugs have improved prognoses for people living with HIV. However, HIV-associated neurocognitive disorders (HAND) persist despite undetectable viral loads. Some ARVs have been linked to neuropsychiatric effects that may contribute to HAND. Synapse loss correlates w...