miR-16-5p Suppresses Progression and Invasion of Osteosarcoma via Targeting at Smad3

BackgroundMicroRNAs are known to regulate carcinogenesis of osteosarcoma. Although, miR-16-5p is known to exert inhibitory effects on several forms of cancers, its effects on the growth and invasion of osteosarcoma have not been studied.MethodsWe collected human osteosarcoma specimens and adjacent t...

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Main Authors: Zhijian Gu (Author), Zhikun Li (Author), Ruijun Xu (Author), Xiaodong Zhu (Author), Ruixi Hu (Author), Yonghua Xue (Author), Wei Xu (Author)
Format: Book
Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
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