Discovery of a Novel Nav1.7 Inhibitor From Cyriopagopus albostriatus Venom With Potent Analgesic Efficacy

Spider venoms contain a vast array of bioactive peptides targeting ion channels. A large number of peptides have high potency and selectivity toward sodium channels. Nav1.7 contributes to action potential generation and propagation and participates in pain signaling pathway. In this study, we descri...

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Main Authors: Yunxiao Zhang (Author), Dezheng Peng (Author), Biao Huang (Author), Qiuchu Yang (Author), Qingfeng Zhang (Author), Minzhi Chen (Author), Mingqiang Rong (Author), Zhonghua Liu (Author)
Format: Book
Published: Frontiers Media S.A., 2018-10-01T00:00:00Z.
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