Systematic Overview of Aristolochic Acids: Nephrotoxicity, Carcinogenicity, and Underlying Mechanisms

• Ngā kaituhi matua: Jiayin Han (Author), Zhong Xian (Author), Yushi Zhang (Author), Jing Liu (Author), Aihua Liang (Author)
• Hōputu: Pukapuka
• I whakaputaina: Frontiers Media S.A., 2019-06-01T00:00:00Z.
• Ngā marau: article
• Urunga tuihono: Connect to this object online.

Aristolochic acids (AAs) are a group of toxins commonly present in the plants of genus Aristolochia and Asarum, which are spread all over the world. Since the 1990s, AA-induced nephropathy (AAN) and upper tract urothelial carcinoma (UTUC) have been reported in many countries. The underlying mechanis...