Using genetically encoded fluorescent biosensors to interrogate ovarian cancer metabolism

• Autores principales: Shree Bose (Autor), Haipei Yao (Autor), Qiang Huang (Autor), Regina Whitaker (Autor), Christopher D. Kontos (Autor), Rebecca A. Previs (Autor), Xiling Shen (Autor)
• Formato: Libro
• Publicado: BMC, 2022-10-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Background Epithelial ovarian cancer (OC) is the most lethal gynecological malignancy and patients present with significant metastatic burden, particularly to the adipose-rich microenvironment of the omentum. Recent evidence has highlighted the importance of metabolic adaptations in enablin...