In Vitro Performance of an Investigational Vibrating-Membrane Nebulizer with Surfactant under Simulated, Non-Invasive Neonatal Ventilation Conditions: Influence of Continuous Positive Airway Pressure Interface and Nebulizer Positioning on the Lung Dose

• Main Authors: Federico Bianco (Author), Elena Pasini (Author), Marcello Nutini (Author), Xabier Murgia (Author), Carolin Stoeckl (Author), Martin Schlun (Author), Uwe Hetzer (Author), Sauro Bonelli (Author), Marta Lombardini (Author), Ilaria Milesi (Author), Marisa Pertile (Author), Stefan Minocchieri (Author), Fabrizio Salomone (Author), Albert Bucholski (Author)
• Format: Book
• Published: MDPI AG, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Non-invasive delivery of nebulized surfactant has been a long-pursued goal in neonatology. Our aim was to evaluate the performance of an investigational vibrating-membrane nebulizer in a realistic non-invasive neonatal ventilation circuit with different configurations. Surfactant (aerosols were gene...