The neutrophil-osteogenic cell axis promotes bone destruction in periodontitis

• Main Authors: Yutaro Ando (Author), Masayuki Tsukasaki (Author), Nam Cong-Nhat Huynh (Author), Shizao Zang (Author), Minglu Yan (Author), Ryunosuke Muro (Author), Kazutaka Nakamura (Author), Masatsugu Komagamine (Author), Noriko Komatsu (Author), Kazuo Okamoto (Author), Kenta Nakano (Author), Tadashi Okamura (Author), Akira Yamaguchi (Author), Kazuyuki Ishihara (Author), Hiroshi Takayanagi (Author)
• Format: Book
• Published: Nature Publishing Group, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The immune-stromal cell interactions play a key role in health and diseases. In periodontitis, the most prevalent infectious disease in humans, immune cells accumulate in the oral mucosa and promote bone destruction by inducing receptor activator of nuclear factor-κB ligand (RANKL) expressi...