Model-Informed Precision Dosing of Vancomycin in Hospitalized Children: Implementation and Adoption at an Academic Children's Hospital

• Main Authors: Adam Frymoyer (Author), Hayden T. Schwenk (Author), Yvonne Zorn (Author), Laura Bio (Author), Jeffrey D. Moss (Author), Bhavin Chasmawala (Author), Joshua Faulkenberry (Author), Srijib Goswami (Author), Ron J. Keizer (Author), Shabnam Ghaskari (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundModel-informed precision dosing (MIPD) can serve as a powerful tool during therapeutic drug monitoring (TDM) to help individualize dosing in populations with large pharmacokinetic variation. Yet, adoption of MIPD in the clinical setting has been limited. Overcoming technologic hurdles that...