Obtaining Gene-Modified HLA-E-Expressing Feeder Cells for Stimulation of Natural Killer Cells

Obtaining Gene-Modified HLA-E-Expressing Feeder Cells for Stimulation of Natural Killer Cells

Human cytomegalovirus (HCMV)-specific adaptive NK cells are capable of recognizing viral peptides presented by HLA-E on infected cells via the NKG2C receptor. Using retroviral transduction, we have generated a K562-cell-based line expressing HLA-E in the presence of the HLA-E-stabilizing peptide, wh...

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Main Authors: Nadezhda A. Alekseeva (Author), Maria A. Streltsova (Author), Julia D. Vavilova (Author), Maria O. Ustiuzhanina (Author), Anastasia I. Palamarchuk (Author), Anna A. Boyko (Author), Nikita D. Timofeev (Author), Alexey I. Popodko (Author), Elena I. Kovalenko (Author)
Format: Book
Published: MDPI AG, 2024-01-01T00:00:00Z.
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3rd Floor Main Library

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