Effect of dexamethasone on carrageenin-induced inflammation in the lung

• Main Authors: S. F. Smith (Author), A. Benjamin (Author), A. Dewar (Author), M. Sheppard (Author), B. Fox (Author), T. Smith (Author), A. Guz (Author), T. D. Tetley (Author)
• Format: Book
• Published: Hindawi Limited, 1995-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To study the anti-inflammatory mechanisms of glucocorticoids, we have compared the effects of intratracheal carrageenin (2.5 mg) on control rats and those in which inflammation was subdued by prior dexamethasone treatment (10 mg/l in drinking water). Inflammation was maximal 48 h post-carrageenin. A...