Single dose of morphine produced a prolonged effect on dopamine neuron activities

• Main Authors: Zhang Kehong (Author), Jin Guo-zhang (Author), Zhang Hai (Author), Zhang Die (Author), Zhen Xuechu (Author)
• Format: Bog
• Udgivet: SAGE Publishing, 2008-11-01T00:00:00Z.
• Fag: article
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<p>Abstract</p> <p>Background</p> <p>Clinical observation and experimental studies have indicated that a single exposure to morphine could induce tolerance and dependence. It has become a concern in clinical antinociceptive practice. However, the underling mechanism rem...