The Specific Copper(II) Chelator TDMQ20 Is Efficient for the Treatment of Wilson's Disease in Mice

• المؤلفون الرئيسيون: Yingshan Zhu (مؤلف), Ying Tang (مؤلف), Lan Huang (مؤلف), Michel Nguyen (مؤلف), Yan Liu (مؤلف), Anne Robert (مؤلف), Bernard Meunier (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

(1) Background: In patients with Wilson's disease, the deficiency of the copper carrier ATP7B causes the accumulation of copper in the liver, brain and various other organs. Lifelong treatment is therefore mandatory, using copper chelators to increase the excretion of copper and to avoid life-t...