The Specific Copper(II) Chelator TDMQ20 Is Efficient for the Treatment of Wilson's Disease in Mice

• Glavni autori: Yingshan Zhu (Autor), Ying Tang (Autor), Lan Huang (Autor), Michel Nguyen (Autor), Yan Liu (Autor), Anne Robert (Autor), Bernard Meunier (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2023-12-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

(1) Background: In patients with Wilson's disease, the deficiency of the copper carrier ATP7B causes the accumulation of copper in the liver, brain and various other organs. Lifelong treatment is therefore mandatory, using copper chelators to increase the excretion of copper and to avoid life-t...