The Effects of Indoxyl Sulfate and Oxidative Stress on the Severity of Peripheral Nerve Dysfunction in Patients with Chronic Kidney Diseases

• Main Authors: Yun-Ru Lai (Author), Ben-Chung Cheng (Author), Chia-Ni Lin (Author), Wen-Chan Chiu (Author), Ting-Yin Lin (Author), Hui-Ching Chiang (Author), Chun-En Aurea Kuo (Author), Chih-Cheng Huang (Author), Cheng-Hsien Lu (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Pieces of evidence support the view that the accumulation of uremic toxins enhances oxidative stress and downstream regulation of signaling pathways, contributing to both endothelial microangiography and cell dysfunction. This study is to address the impact of protein-binding uremic toxins on the se...