Viro-antibody therapy: engineering oncolytic viruses for genetic delivery of diverse antibody-based biotherapeutics

• Váldodahkkit: Roland E. Kontermann (Dahkki), Guy Ungerechts (Dahkki), Dirk M. Nettelbeck (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Cancer therapeutics approved for clinical application include oncolytic viruses and antibodies, which evolved by nature, but were improved by molecular engineering. Both facilitate outstanding tumor selectivity and pleiotropic activities, but also face challenges, such as tumor heterogeneity and lim...