Palmitoylethanolamide reduces granuloma-induced hyperalgesia by modulation of mast cell activation in rats

• Main Authors: Cinelli Maria Pia (Author), Palazzo Enza (Author), Cipriano Mariateresa (Author), Luongo Livio (Author), De Filippis Daniele (Author), de Novellis Vito (Author), Maione Sabatino (Author), Iuvone Teresa (Author)
• Format: Book
• Published: SAGE Publishing, 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>The aim of this study was to obtain evidences of a possible analgesic role for palmitoylethanolamide (PEA) in chronic granulomatous inflammation sustained by mast cell (MC) activation in rats at 96 hours. PEA (200-400-800 μg/mL), locally administered at time 0, r...