NIR spectroscopy coupled with multivariate data analysis in the prediction of the characteristics of mannitol lyophilized cakes

• Main Authors: Alexandru Gavan (Author), Catalina Bogdan (Author), Lucia Rus (Author), Paula Rasteiu (Author), Ioana Toma (Author), Marcela Achim (Author), Sonia Iurian (Author)
• Format: Book
• Published: Amaltea Medical Publishing House, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mannitol is used in freeze-dried products as a bulking agent, consistency enhancer, or stabilizer, having the lowest hygroscopicity among the excipients commonly used as consistency agents, therefore it can be used in the formulation of unstable preparations. Lyophilization is a complex method of dr...