Boosting the Brain Delivery of Atazanavir through Nanostructured Lipid Carrier-Based Approach for Mitigating NeuroAIDS

• Main Authors: Saif Ahmad Khan (Author), Saleha Rehman (Author), Bushra Nabi (Author), Ashif Iqubal (Author), Nida Nehal (Author), Usama A. Fahmy (Author), Sabna Kotta (Author), Sanjula Baboota (Author), Shadab Md (Author), Javed Ali (Author)
• Format: Book
• Published: MDPI AG, 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Atazanavir (ATZ) presents poor brain availability when administered orally, which poses a major hurdle in its use as an effective therapy for the management of NeuroAIDS. The utilization of nanostructured lipid carriers (NLCs) in conjunction with the premeditated use of excipients can be a potential...