Ab-Ligity: identifying sequence-dissimilar antibodies that bind to the same epitope

• Glavni autori: Wing Ki Wong (Autor), Sarah A. Robinson (Autor), Alexander Bujotzek (Autor), Guy Georges (Autor), Alan P. Lewis (Autor), Jiye Shi (Autor), James Snowden (Autor), Bruck Taddese (Autor), Charlotte M. Deane (Autor)
• Format: Knjiga
• Izdano: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Solving the structure of an antibody-antigen complex gives atomic level information of the interactions between an antibody and its antigen, but such structures are expensive and hard to obtain. Alternative experimental sources include epitope mapping and binning experiments, which can be used as a...