The Protective Effects and Mechanism of Doxepin on Radiation-Induced Lung Injury in Rats

• Main Authors: Xinlong Wan (Author), Xuan Shi (Author), Mengke Li (Author), Qing Chen (Author), Chang Xue (Author), Guanghui Li (Author), Yeke Huang (Author), Jingwen Yang (Author), Chan Chen (Author), Zhiyi Wang (Author), Shumei Ma (Author), Xiaodong Liu (Author)
• Format: Book
• Published: SAGE Publishing, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiation-induced lung injuries (RILI) is one of the serious complications of radiotherapy posed by the damage of alveolar cells and inflammation over-reaction. We aimed to investigate the potential protective effects of doxepin on RILI (20 Gy total dose at 3 Gy/min of X-ray irradiation), as well as...