High-fat diet decreases activity of the oxidative phosphorylation complexes and causes nonalcoholic steatohepatitis in mice

• Main Authors: Inmaculada García-Ruiz (Author), Pablo Solís-Muñoz (Author), Daniel Fernández-Moreira (Author), Montserrat Grau (Author), Francisco Colina (Author), Teresa Muñoz-Yagüe (Author), José A. Solís-Herruzo (Author)
• Format: Book
• Published: The Company of Biologists, 2014-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD) is the most frequent histological finding in individuals with abnormal liver-function tests in the Western countries. In previous studies, we have shown that oxidative phosphorylation (OXPHOS) is decreased in individuals with NAFLD, but the cause of this mito...