Bisbenzylisoquinoline Alkaloids of Cissampelos Sympodialis With in Vitro Antiviral Activity Against Zika Virus

• Main Authors: Poliana Gomes da Silva (Author), Aventino H. Fonseca (Author), Malu P. Ribeiro (Author), Taizia D. Silva (Author), Cristiane F. F. Grael (Author), Lindomar J. Pena (Author), Tania M. S. Silva (Author), Eduardo de Jesus Oliveira (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In search of new antiviral compounds against Zika virus we conducted a bioassay-guided fractionation of bisbenzyilisoquinoline alkaloids isolated from Cissampelos sympodialis (Menispermaceae), a medicinal plant species endemic to Brazil. Six subfractions were obtained from a tertiary alkaloidal frac...