Changes in Glucose and Glutamine Lymphocyte Metabolisms Induced by Type I Interferon α

• Main Authors: Francisco Navarro (Author), Aline V. N. Bacurau (Author), Andréa Vanzelli (Author), Marcela Meneguello-Coutinho (Author), Marco C. Uchida (Author), Milton R. Moraes (Author), Sandro S. Almeida (Author), Frederick Wasinski (Author), Carlos C. Barros (Author), Martin Würtele (Author), Ronaldo C. Araújo (Author), Luís F. B. Costa Rosa (Author), Reury F. P. Bacurau (Author)
• Format: Book
• Published: Hindawi Limited, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In lymphocytes (LY), the well-documented antiproliferative effects of IFN-α are associated with inhibition of protein synthesis, decreased amino acid incorporation, and cell cycle arrest. However, the effects of this cytokine on the metabolism of glucose and glutamine in these cells have not been we...