A Validated UHPLC-MS/MS Method to Quantify Eight Antibiotics in Quantitative Dried Blood Spots in Support of Pharmacokinetic Studies in Neonates

• Main Authors: Qian Liu (Author), Lanyu Liu (Author), Yu Yuan (Author), Feifan Xie (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2023-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Objectives: Conduction of pharmacokinetic (PK) study in pediatric patients is challenging due to blood sampling limits. The dried blood spots (DBS) method represents a potential matrix for microsampling in support of PK studies in children. Herein, we used the Capitainer^® qDBS...