Ileal Bile Acid Transporter Inhibition Reduces Post-Transplant Diarrhea and Growth Failure in FIC1 Disease-A Case Report

• Main Authors: Johanna Ohlendorf (Author), Imeke Goldschmidt (Author), Norman Junge (Author), Tobias Laue (Author), Hamoud Nasser (Author), Elmar Jäckel (Author), Frauke Mutschler (Author), Eva-Doreen Pfister (Author), Diran Herebian (Author), Verena Keitel (Author), Ulrich Baumann (Author)
• Format: Book
• Published: MDPI AG, 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Familial intrahepatic cholestasis 1 (FIC1) disease is a genetic disorder characterized by hepatic and gastrointestinal disease due to <i>ATP8B1</i> deficiency, often requiring liver transplantation (LT). Extrahepatic symptoms, such as diarrhea, malabsorption, and failure to thrive, do no...