Accumulation of senescent cells in the stroma of aged mouse ovary

• Main Authors: Natsumi MARUYAMA (Author), Isuzu FUKUNAGA (Author), Tomoaki KOGO (Author), Tsutomu ENDO (Author), Wataru FUJII (Author), Masami KANAI-AZUMA (Author), Kunihiko NAITO (Author), Koji SUGIURA (Author)
• Format: Book
• Published: The Society for Reproduction and Development, 2023-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Senescent cells play a detrimental role in age-associated pathogenesis by producing factors involved in senescence-associated secretory phenotype (SASP). The present study was conducted to examine the possibility that senescent cells are present in aged ovaries and, if so, to determine the tissue re...