Overexpression of microRNA-722 fine-tunes neutrophilic inflammation by inhibiting Rac2 in zebrafish

• Main Authors: Alan Y. Hsu (Author), Decheng Wang (Author), Theodore Gurol (Author), Wenqing Zhou (Author), Xiaoguang Zhu (Author), Hsiu-Yi Lu (Author), Qing Deng (Author)
• Format: Book
• Published: The Company of Biologists, 2017-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neutrophilic inflammation is essential for defending against invading pathogens, but can also be detrimental in many clinical settings. The hematopoietic-specific small Rho-GTPase Rac2 regulates multiple pathways that are essential for neutrophil activation, including adhesion, migration, degranulat...