In Silico, In Vitro, and In Vivo Evaluation of Caffeine-Coated Nanoparticles as a Promising Therapeutic Avenue for AML through NF-Kappa B and TRAIL Pathways Modulation

• Main Authors: Muhammad Hamid Siddique (Author), Sidra Bukhari (Author), Inam Ullah Khan (Author), Asiya Essa (Author), Zain Ali (Author), Usama Sabir (Author), Omiya Ayoub (Author), Haleema Saadia (Author), Muhammad Yaseen (Author), Aneesa Sultan (Author), Iram Murtaza (Author), Philip G. Kerr (Author), Mashooq Ahmad Bhat (Author), Mariam Anees (Author)
• Format: Book
• Published: MDPI AG, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Advancements in nanoscience have led to a profound paradigm shift in the therapeutic applications of medicinally important natural drugs. The goal of this research is to develop a nano-natural product for efficient cancer treatment. Methods and Results: For this purpose, mesoporous silic...